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GHK-Cu and Extracellular Matrix Research Research confirms that GHK stimulates synthesis of collagen, dermatan sulfate, chondroitin sulfate, and the small proteoglycan decorin, while also modulating metalloproteinase activity and their inhibitors making it a key compound in extracellular matrix research

The GPx mimicking activity of DSePA was studied under in vitro conditions using a GSH-NADH-GR coupled assay

This cemented their role as a core therapy for this condition (Packer et al., 2020

Its recommendation will inevitably be interpreted as an endorsement of broader clinical use